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KMID : 0882420050680060638
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Korean Journal of Medicine
2005 Volume.68 No. 6 p.638 ~ p.646
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Relationship of anemia and uric acid with clinical outcomes in congestive heart failure
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한창희:Han Chang-Hee
온영근:On Young-Keun/서존:Suh John/김도회:Kim Do-Hoi/방덕원:Bang Duk-Won/현민수:Hyon Min-Su/김성구:Kim Sung-Koo/권영주:Kwon Young-Joo
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Abstract
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Backgroud : Serum uric acid (UA) and anemia could be a valid and useful prognostic marker of |
chronic heart failure (CHF). We investigated the relationship of anemia and UA with clinical |
outcomes in CHF patients.
Methods : We analyzed 109 patients with congestive heart failure between August 2001 and October
2002 (age 67+15 years, follow-up 14+5 months). We distributed the patients into 3 groups according to |
hematocrit (Het) level [Het group 1 (Het <30%, n=21), Het group 2 (Het 30~38%, n=49), Het group 3
(Het >33%, n=39)] and into 3 groups according to serum uric acid (UA) level [UA group I (UA <52
mg/dL, n-20), UA group Il (UA 52~75 mg/dL, n=25), UA group IIl (UA >75 mg/dL, n=20)]. Primary
end point were rehospitalization resulting from aggravation of CHF and all-cause of death.
Results : Among the groups according to Het level, readmission rates were 57.1%, 286%, 15.4%,
respectively (p<0.05). Among men, readmission rates were 82.3%, 22.2%, 143%, respectively
(p<005). No significant difference in death rate was observed among the 3 groups. Among the
groups according to UA level, there was no significant difference in readmission rates. Death rates |
were 5%, 8%, 36%, respectively (p<0.05) and there was significant difference in death rate especially
among male patients.
Conclusion : In male patients, lower hematocrit level was associated with higher readmission rate
and higher serum uric acid level was associated with death rate.(Korean | Med 63638646, 2005)
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KEYWORD
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Uric acid, Anemia, Heart failure
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